微软已经列出了可能会在SP2里出现问题的程序名单。这不是一份和SP2不兼容的程序名单，但是名单上这些程序有可能在安装SP2的机子里不能正常工作或者时和以往的运转不同。
SP2引入了许多新的特色来帮助提高WindowsXP的性能和安全，名单上的有些程序有可能是和Windows防火墙有冲突。你可以通过搜索微软的知识库（Microsoft Knowledge Base）查询SP2新特色对这些程序都有那些影响。（提示：用WINXPSP2作为搜索关键字）
名单中许多软件的供应商将会发行补丁来解决他们的软件可能出现的问题。例如Neowin UXTheme MultiPatcher，名单上的版本号是 V1.5.1，但是在SP2发行后Neowin已经把程序的版本升级到version 2.0。
Program Version Vendor
App Version ISV
Star Trek StarFleet Command III v1.0 Activision
Medieval Total War 1 Activision
Pagemaker 7 Adobe
PageMaker (German) 6.5 Adobe
Photoshop Elements 2 Adobe
Ad-Shield 3 Ad-sheild
ERDisk for AD 6.7.128.0 Aelita
Nero 6 Ultra 6 Ahead
Nero Bruning ROM 5.5.6 Ahead
Al Mawrad (Arabic) 2003 Al Ariss
PhotoClick --- Al Maalin
AOL 9 AOL
AOL Toolkit 1.13.2 AOL
Uno 1 Aris Buenaventura
Dead Man's Hand 1 Atari
MotoRacer 3 Atari
Scrabble v3.0 Atari
Unreal II 1 Atari
Unreal Tournament 2003 1 Atari
Unreal Tournament Game of the Year Edition 1 Atari
Extra Enterprise 2000 2000 --- Attachmate
Extra Personal Client 6.5 --- Attachmate
Extra! Bundle for TCP/IP 6.6 --- Attachmate
KEA! 340 v5.1 --- Attachmate
Command Antivirus 4.9 authentium
AutoCAD 2004 2004 --- Autodesk
bv-Admin Mobile 7 --- Bind View
StarCraft 1.05 Blizzard
BitDefender 7.2 Blizzard
Starcraft v1.11 Blizzard
Warcraft III: Reign of Chaos Collector's Edition v 1.0 Blizzard
Patrol for windows 2000 3.4.0.11 --- BMC
Word Perfect Family Pack 5 - Encyclopedia Britannica Ready Reference 2003 Britannica
WISO Sparbuch 2004 Buhl
InnoculateIT --- CA
MpegCraft DVD x Caropus
Citrix ICA client 7.1 Citrix
FileMaker Pro (German) 5 Claris
ArcServe 6.61 Computer Associates
ArcServe 7.0 --- Computer Associates
BrightStor ArcServe Backup 9.0 --- Computer Associates
eTrust 7 Computer Associates
eTrust 6.0.100 --- Computer Associates
Etrust EZArmor AE Test Computer Associates
Corel Draw 9 - PhotoPaint (German) 9 Corel
WordPerfect Office 11 Corel
1st nd Grade Excelerator Curious George Studio 1 --- Countertop Software
Serious Sam: The Second Encounter 1 Croteam
Retrospect Client x Dantz
Dave's Quick Search Toolbar 3.16 Dave Bau http://notesbydave.com/toolbar/doc.htm
Diet KaZaa 2.52 Diet KaZaa
The Lion King Animated Storybook 1 Disney
DivxPlayer 2.5.3 Divx
Command & Conquer Generals --- EA Games
Command & Conquer Generals Zero Hour --- EA Games
Earth & Beyond v.1 EA Games
Need for Speed Hot Pursuit 2 1 EA Games